Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate receptor 2 | 0.2064 | 0.8025 | 0.8025 |
Loa Loa (eye worm) | hypothetical protein | 0.1388 | 0.3651 | 0.4062 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.2213 | 0.8988 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Echinococcus granulosus | glutamate receptor 4 | 0.1388 | 0.3651 | 0.3651 |
Loa Loa (eye worm) | hypothetical protein | 0.1388 | 0.3651 | 0.4062 |
Brugia malayi | Glutamate receptor 2 precursor | 0.2213 | 0.8988 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Loa Loa (eye worm) | hypothetical protein | 0.1388 | 0.3651 | 0.4062 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Echinococcus granulosus | glutamate receptor 2 | 0.2064 | 0.8025 | 0.8025 |
Echinococcus granulosus | glutamate receptor 1 | 0.1388 | 0.3651 | 0.3651 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.1694 | 0.5626 | 0.5626 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.1694 | 0.5626 | 0.5626 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Echinococcus multilocularis | glutamate receptor 4 | 0.1388 | 0.3651 | 0.3651 |
Echinococcus multilocularis | glutamate receptor 2 | 0.2213 | 0.8988 | 0.8988 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.2369 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.2369 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0981 | 0.1012 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.2369 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0981 | 0.1012 | 0.1012 |
Brugia malayi | Glutamate receptor 1 precursor | 0.2213 | 0.8988 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | 0 | Inhibition of alpha1H T-type calcium channel Cav3.2 expressed in Xenopus unfertilized oocytes at 100 uM by two-electrode voltage clamp method | ChEMBL. | 17074493 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.