Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0526 | 0.2524 | 0.2524 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0601 | 0.3508 | 0.1316 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0601 | 0.3508 | 0.1316 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0601 | 0.3508 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0526 | 0.2524 | 0.2524 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0378 | 0.059 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.1095 | 1 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0601 | 0.3508 | 0.1316 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0601 | 0.3508 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.1095 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0601 | 0.3508 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.1095 | 1 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.1095 | 1 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.1095 | 1 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0526 | 0.2524 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0601 | 0.3508 | 0.3508 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0601 | 0.3508 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0601 | 0.3508 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IZ (functional) | = 10 mm | Antifungal activity against Candida albicans NCIM no. 300 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 10 mm | Antifungal activity against Candida albicans NCIM no. 300 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 11 mm | Antifungal activity against Trichophyton mentagrophytes after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 13 mm | Antifungal activity against Aspergillus fumigatus NCIM no. 902 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 15 mm | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
IZ (functional) | = 15 mm | Antibacterial activity against Streptococcus pyogenes after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
IZ (functional) | = 15 mm | Antifungal activity against Aspergillus flavus NCIM no. 524 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 15 mm | Antifungal activity against Penicillium marneffei after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
IZ (functional) | = 16 mm | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
IZ (functional) | = 17 mm | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
IZ (functional) | = 17 mm | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
IZ (functional) | = 19 mm | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 6.25 ug ml-1 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 6.25 ug ml-1 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 6.25 ug ml-1 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 6.25 ug ml-1 | Antifungal activity against Penicillium marneffei after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
MIC (functional) | = 12.5 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 12.5 ug ml-1 | Antibacterial activity against Streptococcus pyogenes after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 12.5 ug ml-1 | Antifungal activity against Aspergillus fumigatus NCIM no. 902 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
MIC (functional) | = 12.5 ug ml-1 | Antifungal activity against Aspergillus flavus NCIM no. 524 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
MIC (functional) | = 12.5 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by disc diffusion method | ChEMBL. | 17007964 |
MIC (functional) | = 25 ug ml-1 | Antifungal activity against Trichophyton mentagrophytes after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
MIC (functional) | = 25 ug ml-1 | Antifungal activity against Candida albicans NCIM no. 300 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
MIC (functional) | = 25 ug ml-1 | Antifungal activity against Candida albicans NCIM no. 300 after 3 to 4 days by serial plate dilution method | ChEMBL. | 17007964 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.