Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | poly(ADP-ribose) glycohydrolase, putative | 0.0787 | 1 | 1 |
Toxoplasma gondii | poly(ADP-ribose) glycohydrolase | 0.0787 | 1 | 1 |
Schistosoma mansoni | poly(ADP-ribose) glycohydrolase | 0.0787 | 1 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.0787 | 1 | 0.5 |
Echinococcus granulosus | polyADP ribose glycohydrolase | 0.0787 | 1 | 0.5 |
Loa Loa (eye worm) | Poly(ADP-ribose) glycohydrolase | 0.0787 | 1 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0787 | 1 | 1 |
Echinococcus multilocularis | poly(ADP ribose) glycohydrolase | 0.0787 | 1 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.0787 | 1 | 0.5 |
Trypanosoma brucei | poly(ADP-ribose) glycohydrolase, putative | 0.0787 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GE (functional) | = 10 % | Evaluated for the effects on the gastric emptying rates of phenol red semisolid meal through the stomach in rats, at a dose of 2.0 mg/Kg administered perorally. | ChEMBL. | 2139471 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.