Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0508 | 1 | 1 |
Brugia malayi | Sodium:solute symporter family protein | 0.013 | 0 | 0.5 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0508 | 1 | 1 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.013 | 0 | 0.5 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0508 | 1 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0508 | 1 | 1 |
Brugia malayi | GH02984p | 0.013 | 0 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.0508 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.0508 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.0508 | 1 | 1 |
Onchocerca volvulus | 0.013 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.0508 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 14 uM | Binding affinity to human alpha1-acid glycoprotein at 30 uM | ChEMBL. | 17507228 |
Activity (binding) | = 14 uM | Binding affinity to human alpha1-acid glycoprotein at 30 uM | ChEMBL. | 17507228 |
Activity (binding) | = 17 uM | Binding affinity to 30 uM human serum albumin at 30 uM | ChEMBL. | 17507228 |
Activity (binding) | = 17 uM | Binding affinity to 30 uM human serum albumin at 30 uM | ChEMBL. | 17507228 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.