Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0261 | 0 | 0.5 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.1024 | 1 | 1 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.1024 | 1 | 1 |
Brugia malayi | GH02984p | 0.0261 | 0 | 0.5 |
Brugia malayi | Sodium:solute symporter family protein | 0.0261 | 0 | 0.5 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.1024 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.1024 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.1024 | 1 | 1 |
Schistosoma mansoni | inositol transporter | 0.1024 | 1 | 1 |
Onchocerca volvulus | 0.0261 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 0.1024 | 1 | 1 |
Schistosoma mansoni | inositol transporter | 0.1024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI (functional) | = 30 % | Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay | ChEMBL. | 17561405 |
GI (functional) | = 30 % | Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay | ChEMBL. | 17561405 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.