Detailed information for compound 434775

Basic information

Technical information
  • TDR Targets ID: 434775
  • Name: 1-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phen yl]-3-(4-methylphenyl)sulfonylurea
  • MW: 454.926 | Formula: C23H19ClN2O4S
  • H donors: 2 H acceptors: 4 LogP: 5.37 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc1ccc(cc1)C(=O)/C=C\c1ccc(cc1)Cl
  • InChi: 1S/C23H19ClN2O4S/c1-16-2-13-21(14-3-16)31(29,30)26-23(28)25-20-11-7-18(8-12-20)22(27)15-6-17-4-9-19(24)10-5-17/h2-15H,1H3,(H2,25,26,28)/b15-6+
  • InChiKey: JGMSODYZANAVDM-GIDUJCDVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]-3-(p-tolylsulfonyl)urea
  • 1-[4-[(E)-3-(4-chlorophenyl)-1-oxoallyl]phenyl]-3-(p-tolylsulfonyl)urea
  • 1-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]-3-(4-methylphenyl)sulfonyl-urea
  • 1-[4-[(E)-3-(4-chlorophenyl)acryloyl]phenyl]-3-tosyl-urea
  • 3-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]-1-(4-methylphenyl)sulfonylurea
  • 3-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]-1-(4-methylphenyl)sulfonyl-urea
  • 3-[4-[(E)-3-(4-chlorophenyl)-1-oxoprop-2-enyl]phenyl]-1-(4-methylphenyl)sulfonylurea
  • 3-[4-[(E)-3-(4-chlorophenyl)acryloyl]phenyl]-1-(4-methylphenyl)sulfonyl-urea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni amine GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0.9825 0.5
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni alpha-1 adrenergic receptor 0.001 0.9825 0.5
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0.9825 0.5
Brugia malayi Dopamine receptor 0.001 0.9825 0.5
Echinococcus multilocularis g-protein coupled receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide Y receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus granulosus neuropeptides capa receptor 0.001 0.9825 0.5
Schistosoma mansoni adenoreceptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis serotonin receptor 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide receptor A26 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0.9825 0.5
Schistosoma mansoni opsin-like receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0.9825 0.5
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0.9825 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.9825 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.9825 0.5
Brugia malayi RE15519p 0.001 0.9825 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.9825 0.5
Schistosoma mansoni opsin-like receptor 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.9825 0.5
Echinococcus multilocularis fmrfamide receptor 0.001 0.9825 0.5
Brugia malayi putative neuropeptide receptor NPR1 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.9825 0.5
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0.9825 0.5
Echinococcus multilocularis serotonin receptor 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide receptor 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide receptor 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide Y receptor 0.001 0.9825 0.5
Echinococcus multilocularis allatostatin A receptor 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus orexin receptor type 2 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus granulosus fmrfamide receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0.9825 0.5
Brugia malayi larval opioid receptor 0.001 0.9825 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0.9825 0.5
Echinococcus multilocularis fmrfamide receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0.9825 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) TYRA-2 protein 0.001 0.9825 0.5
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Brugia malayi Serotonin receptor 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide receptor 0.001 0.9825 0.5
Echinococcus granulosus g protein coupled receptor 0.001 0.9825 0.5
Leishmania major hypothetical protein, conserved 0.0002 0 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni growth hormone secretagogue receptor 0.001 0.9825 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.9825 0.5
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide s receptor 0.001 0.9825 0.5
Schistosoma mansoni hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.9825 0.5
Echinococcus granulosus g protein coupled receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Loa Loa (eye worm) follicle stimulating hormone receptor 0.001 0.9825 0.5
Schistosoma mansoni opsin-like receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus g protein coupled receptor 0.001 0.9825 0.5
Brugia malayi neuropeptide F receptor 0.001 0.9825 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Brugia malayi follicle stimulating hormone receptor 0.001 0.9825 0.5
Brugia malayi sulfakinin receptor protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus somatostatin receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus multilocularis orexin receptor type 2 0.001 0.9825 0.5
Schistosoma mansoni peptide (allatostatin)-like receptor 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0.9825 0.5
Onchocerca volvulus Neuropeptide F receptor homolog 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis g protein coupled receptor 0.001 0.9825 0.5
Brugia malayi AKH receptor 0.001 0.9825 0.5
Echinococcus granulosus allatostatin A receptor 0.001 0.9825 0.5
Echinococcus granulosus g-protein coupled receptor 0.001 0.9825 0.5
Schistosoma mansoni amine GPCR 0.001 0.9825 0.5
Brugia malayi neuropeptide F receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis g protein coupled receptor 0.001 0.9825 0.5
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0.9825 0.5
Schistosoma mansoni hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis G protein coupled receptor 139 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide receptor 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide receptor A26 0.001 0.9825 0.5
Mycobacterium ulcerans oxidase 0.0011 1 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni amine GPCR 0.001 0.9825 0.5
Brugia malayi GnHR receptor homolog 0.001 0.9825 0.5
Echinococcus granulosus neuropeptides capa receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus sex peptide receptor 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.9825 0.5
Trypanosoma cruzi multicopper oxidase, putative 0.0002 0 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Brugia malayi G protein-coupled receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide receptor 0.001 0.9825 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus G protein coupled receptor 139 0.001 0.9825 0.5
Brugia malayi Dopamine receptor protein 1 0.001 0.9825 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine receptor 0.001 0.9825 0.5
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0.9825 0.5
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.9825 0.5
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0.9825 0.5
Brugia malayi Serotonin receptor 0.001 0.9825 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.9825 0.5
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0.9825 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.9825 0.5
Brugia malayi putative neuropeptide receptor 0.001 0.9825 0.5
Trypanosoma cruzi multicopper oxidase, putative 0.0002 0 0.5
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0.9825 0.5
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0.9825 0.5
Trypanosoma brucei hypothetical protein, conserved 0.0002 0 0.5
Trypanosoma brucei multicopper oxidase, putative 0.0002 0 0.5
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide receptor 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni amine GPCR 0.001 0.9825 0.5
Echinococcus granulosus serotonin receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptide s receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni myosin xvIII 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.9825 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Brugia malayi Melatonin receptor type 1A 0.001 0.9825 0.5
Schistosoma mansoni hypothetical protein 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Brugia malayi G-protein coupled receptor 0.001 0.9825 0.5
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0.9825 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis g protein coupled receptor 0.001 0.9825 0.5
Onchocerca volvulus 0.001 0.9825 0.5
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.001 0.9825 0.5
Echinococcus granulosus hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.001 0.9825 0.5
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis sex peptide receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni histamine h1 receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni amine GPCR 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Brugia malayi ORL1-like opioid receptor 0.001 0.9825 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.001 0.9825 0.5
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.9825 0.5
Schistosoma mansoni hypothetical protein 0.001 0.9825 0.5
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0.9825 0.5
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0.9825 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.9825 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.9825 0.5
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.001 0.9825 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.9825 0.5
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.001 0.9825 0.5
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0.9825 0.5
Echinococcus granulosus neuropeptide receptor 0.001 0.9825 0.5
Echinococcus multilocularis somatostatin receptor 0.001 0.9825 0.5
Brugia malayi Dopamine receptor protein 2 0.001 0.9825 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.9825 0.5
Brugia malayi hypothetical protein 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine receptor 0.001 0.9825 0.5
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0.9825 0.5
Schistosoma mansoni biogenic amine receptor 0.001 0.9825 0.5
Brugia malayi G-protein coupled receptor 0.001 0.9825 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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