Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0108 | 0 | 0.5 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.3731 | 1 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0427 | 0.0878 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0321 | 0.0586 | 1 |
Onchocerca volvulus | 0.0321 | 0.0586 | 0.0725 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0321 | 0.0586 | 1 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.3731 | 1 | 1 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.1592 | 0.4094 | 0.4094 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.3731 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0121 | 0.0036 | 0.0036 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0108 | 0 | 0.5 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0108 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.0586 | 0.0586 |
Trichomonas vaginalis | conserved hypothetical protein | 0.3731 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0427 | 0.0878 | 0.0878 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.3731 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.0575 | 0.0575 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.3731 | 1 | 1 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.3731 | 1 | 0.5 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0427 | 0.0878 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.0302 | 0.0302 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0427 | 0.0878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.0586 | 0.0586 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0108 | 0 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0427 | 0.0878 | 0.0878 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.3731 | 1 | 0.5 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.1592 | 0.4094 | 0.4094 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0108 | 0 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0321 | 0.0586 | 0.0586 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.3731 | 1 | 0.5 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0108 | 0 | 0.5 |
Onchocerca volvulus | 0.0964 | 0.2362 | 1 | |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.3731 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.