Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tissue type plasminogen activator | 0.0653 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0653 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0495 | 0.5763 | 0.2037 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0653 | 1 | 1 |
Onchocerca volvulus | 0.0653 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0495 | 0.5763 | 0.2037 |
Brugia malayi | Trypsin family protein | 0.0495 | 0.5763 | 0.2037 |
Onchocerca volvulus | 0.0495 | 0.5763 | 0.5763 | |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0653 | 1 | 0.5 |
Toxoplasma gondii | kringle domain-containing protein | 0.0653 | 1 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.0638 | 0.9588 | 0.9225 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0495 | 0.5763 | 0.2037 |
Toxoplasma gondii | PAN domain-containing protein | 0.0638 | 0.9588 | 0.9225 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0653 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0653 | 1 | 1 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0653 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0495 | 0.5763 | 0.2037 |
Loa Loa (eye worm) | hypothetical protein | 0.0466 | 0.4989 | 0.0583 |
Onchocerca volvulus | Arrow homolog | 0.0454 | 0.4679 | 0.4679 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0653 | 1 | 1 |
Brugia malayi | Kringle domain containing protein | 0.0653 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0653 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.