Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 42 % | Inhibition of metallo-beta-lactamases FEZ1 assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 82 % | Inhibition of metallo-beta-lactamases Bc2 assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 90 % | Inhibition of metallo-beta-lactamases CphA assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 90 % | Inhibition of metallo-beta-lactamases CphA assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 92 % | Inhibition of metallo-beta-lactamases IMP1 assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 92 % | Inhibition of metallo-beta-lactamases IMP1 assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Activity (binding) | = 103 % | Inhibition of metallo-beta-lactamases L1 assessed as residual activity at 100 uM | ChEMBL. | 17157014 |
Inhibition (binding) | = 58 % | Inhibition of metallo-beta-lactamases FEZ1 | ChEMBL. | 17157014 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.