Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | 0 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 | ChEMBL. | 17493808 |
IC50 (functional) | 0 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 | ChEMBL. | 17493808 |
IC50 (functional) | = 407 uM | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 | ChEMBL. | 17493808 |
IC50 (functional) | = 407 uM | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 | ChEMBL. | 17493808 |
IC50 (functional) | = 535 uM | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 | ChEMBL. | 17493808 |
IC50 (functional) | = 535 uM | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 | ChEMBL. | 17493808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.