Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0003 | 0.0015 | 0.0015 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0157 | 0.9985 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0003 | 0.0015 | 0.0016 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0154 | 0.9781 | 0.9781 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0154 | 0.9781 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0003 | 0.0015 | 0.0015 |
Brugia malayi | olfactory channel protein osm-9 | 0.0003 | 0.0015 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0003 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0.0015 | 1 |
Echinococcus granulosus | ankyrin repeat protein | 0.0154 | 0.9781 | 0.9796 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0003 | 0.0015 | 0.0015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 13 uM | Inhibition of Clostridium botulinum A recombinant light chain protease LC/A by FRET assay | ChEMBL. | 17951059 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.