Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | tachykinin receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0253 | 0.173 | 0.173 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0308 | 0.217 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0308 | 0.217 | 0.217 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0308 | 0.217 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0308 | 0.217 | 0.217 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0308 | 0.217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.4634 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.4634 | 0.4634 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0308 | 0.217 | 1 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.1285 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0253 | 0.173 | 0.3733 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0308 | 0.217 | 0.217 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0308 | 0.217 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0308 | 0.217 | 0.217 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0308 | 0.217 | 0.217 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.1285 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0308 | 0.217 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0308 | 0.217 | 0.4682 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0308 | 0.217 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0308 | 0.217 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.1285 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0308 | 0.217 | 0.217 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0308 | 0.217 | 0.217 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0308 | 0.217 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0308 | 0.217 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0308 | 0.217 | 0.5 |
Brugia malayi | hypothetical protein | 0.0615 | 0.4634 | 1 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0308 | 0.217 | 0.217 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0308 | 0.217 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0308 | 0.217 | 1 |
Onchocerca volvulus | 0.0037 | 0 | 0.5 | |
Plasmodium falciparum | protein kinase 5 | 0.0308 | 0.217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.2143 | 0.2143 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0308 | 0.217 | 0.217 |
Echinococcus granulosus | cyclin dependent kinase | 0.0308 | 0.217 | 0.217 |
Giardia lamblia | Kinase, CMGC CDK | 0.0308 | 0.217 | 1 |
Brugia malayi | cell division control protein 2 homolog | 0.0308 | 0.217 | 0.4682 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0308 | 0.217 | 0.217 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0308 | 0.217 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0308 | 0.217 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0308 | 0.217 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0308 | 0.217 | 0.217 |
Plasmodium vivax | protein kinase Crk2 | 0.0308 | 0.217 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.