Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cdc2-related kinase 1 | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.2203 | 0.1439 | 0.1439 |
Plasmodium vivax | protein kinase Crk2 | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.4528 | 0.4182 | 0.4182 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.2203 | 0.1439 | 0.1439 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2203 | 0.1439 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.2203 | 0.1439 | 0.5 |
Brugia malayi | cell division control protein 2 homolog | 0.2203 | 0.1439 | 0.3441 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.9458 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2203 | 0.1439 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.2203 | 0.1439 | 0.3441 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.2203 | 0.1439 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.9458 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.4528 | 0.4182 | 0.4182 |
Brugia malayi | hypothetical protein | 0.4528 | 0.4182 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.2203 | 0.1439 | 0.5 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.2203 | 0.1439 | 0.5 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.9458 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2179 | 0.1411 | 0.1411 |
Giardia lamblia | Kinase, CMGC CDK | 0.2203 | 0.1439 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.2203 | 0.1439 | 0.1439 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.2203 | 0.1439 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2203 | 0.1439 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.2203 | 0.1439 | 0.5 |
Plasmodium falciparum | protein kinase 5 | 0.2203 | 0.1439 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.2203 | 0.1439 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.2203 | 0.1439 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.