Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.2429 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.2429 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.2429 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.2429 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.2429 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.2429 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.2429 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.2429 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 14 % | Effect on T3S in Yersinia pseudotuberculosis 3 pIB29 assessed as inhibition of light emission at 10 uM by luciferase reporter gene assay | ChEMBL. | 17975903 |
Inhibition (binding) | = 29 % | Effect on T3S in Yersinia pseudotuberculosis 3 pIB29 assessed as inhibition of light emission at 20 uM by luciferase reporter gene assay | ChEMBL. | 17975903 |
Inhibition (binding) | = 64 % | Effect on T3S in Yersinia pseudotuberculosis 3 pIB29 assessed as inhibition of light emission at 50 uM by luciferase reporter gene assay | ChEMBL. | 17975903 |
Inhibition (binding) | = 78 % | Effect on T3S in Yersinia pseudotuberculosis 3 pIB29 assessed as inhibition of light emission at 100 uM by luciferase reporter gene assay | ChEMBL. | 17975903 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.