Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histone deacetylase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | dihydropyridine-sensitive l-type calcium channel | 0.008 | 0.0083 | 0.0105 |
Echinococcus granulosus | histone deacetylase 1 | 0.0077 | 0.0047 | 0.0022 |
Loa Loa (eye worm) | calcium channel | 0.0076 | 0.0038 | 0.0038 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0077 | 0.0047 | 0.0022 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.0047 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.015 | 0.0259 |
Trypanosoma brucei | histone deacetylase 1 | 0.0077 | 0.0047 | 0.5 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.0165 | 0.1135 | 0.2524 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0077 | 0.0047 | 0.0047 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0076 | 0.0038 | 0.0038 |
Echinococcus granulosus | voltage dependent calcium channel subunit | 0.0363 | 0.3578 | 0.8137 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.0047 | 0.0022 |
Schistosoma mansoni | high voltage-activated calcium channel beta subunit 2 | 0.0428 | 0.4388 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0077 | 0.0047 | 0.0047 |
Echinococcus granulosus | high voltage activated calcium channel beta | 0.0428 | 0.4388 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.0077 | 0.0047 | 0.0022 |
Echinococcus multilocularis | high voltage activated calcium channel beta | 0.0428 | 0.4388 | 1 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0077 | 0.0047 | 0.0047 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.0047 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.0047 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Loa Loa (eye worm) | voltage-dependent calcium channel beta 2a subunit | 0.0883 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0047 | 0.0047 |
Plasmodium falciparum | histone deacetylase 1 | 0.0077 | 0.0047 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0077 | 0.0047 | 0.0047 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Echinococcus granulosus | voltage dependent calcium channel subunit | 0.0165 | 0.1135 | 0.2524 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0038 | 0.0038 |
Giardia lamblia | Histone deacetylase | 0.0077 | 0.0047 | 0.5 |
Schistosoma mansoni | serine-rich repeat protein | 0.0085 | 0.015 | 0.0259 |
Schistosoma mansoni | dihydropyridine-sensitive l-type calcium channel | 0.0158 | 0.1052 | 0.2332 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0077 | 0.0047 | 0.5 |
Entamoeba histolytica | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0077 | 0.0047 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0077 | 0.0047 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.0047 | 0.5 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.0363 | 0.3578 | 0.8137 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.0047 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0077 | 0.0047 | 0.0047 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.0047 | 0.5 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0077 | 0.0047 | 0.0022 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.0047 | 0.0022 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.