Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.0665 | 0.0656 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.001 | 0.001 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.022 | 0.021 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.1924 | 1 | 1 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.0665 | 0.0656 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.0665 | 0.0665 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.1924 | 1 | 0.5 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.1924 | 1 | 0.5 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.0665 | 0.0656 |
Echinococcus multilocularis | 0.1924 | 1 | 1 | |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.022 | 0.021 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.084 | 0.4198 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.022 | 0.021 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.1924 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.084 | 0.4198 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.0665 | 0.0656 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.1924 | 1 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.001 | 0.001 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.1924 | 1 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.022 | 0.022 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.022 | 0.021 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.