Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.022 | 0.021 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.1924 | 1 | 1 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.1924 | 1 | 0.5 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.1924 | 1 | 1 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.022 | 0.022 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Echinococcus multilocularis | 0.1924 | 1 | 1 | |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.0665 | 0.0656 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.001 | 0.001 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.0665 | 0.0656 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.1924 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.022 | 0.021 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.001 | 0.001 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.084 | 0.4198 | 0.5 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.1924 | 1 | 0.5 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.0665 | 0.0656 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.022 | 0.021 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.0665 | 0.0665 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.0665 | 0.0656 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0214 | 0.0205 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1924 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1924 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.084 | 0.4198 | 0.5 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.1924 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.022 | 0.021 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.