Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.0028 | 0.0028 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.1899 | 0.1899 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0626 | 0.06 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.0711 | 1 | 0.5 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.1899 | 0.1877 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.031 | 0.3886 | 0.5 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.1899 | 0.1877 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0626 | 0.06 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.0711 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.031 | 0.3886 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.0711 | 1 | 1 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0626 | 0.06 |
Echinococcus multilocularis | 0.0711 | 1 | 1 | |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0626 | 0.0626 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.0711 | 1 | 1 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.0711 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.1899 | 0.1877 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.0028 | 0.0028 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.1899 | 0.1877 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0626 | 0.06 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.0711 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.