Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0626 | 0.06 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus multilocularis | 0.0711 | 1 | 1 | |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.1899 | 0.1877 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0626 | 0.06 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.1899 | 0.1877 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.0711 | 1 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.1899 | 0.1899 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.1899 | 0.1877 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.0711 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0626 | 0.0626 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.0711 | 1 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.0711 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0611 | 0.0585 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0626 | 0.06 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0711 | 1 | 0.5 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.0711 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0626 | 0.06 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.031 | 0.3886 | 0.5 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.0711 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.1899 | 0.1877 |
Mycobacterium ulcerans | hypothetical protein | 0.031 | 0.3886 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.