Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.4253 | 1 | 0.5 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.4253 | 1 | 1 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.4253 | 1 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0098 | 0.0093 |
Echinococcus multilocularis | 0.4253 | 1 | 1 | |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0098 | 0.0098 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0095 | 0.0091 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0095 | 0.0091 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.4253 | 1 | 1 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.4253 | 1 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.4253 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.0296 | 0.0292 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.0004 | 0.0004 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.0296 | 0.0292 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.4253 | 1 | 0.5 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.4253 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0098 | 0.0093 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.4253 | 1 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.0004 | 0.0004 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.4253 | 1 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.0296 | 0.0296 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.0296 | 0.0292 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.4253 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0098 | 0.0093 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.4253 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1857 | 0.4291 | 0.5 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.0296 | 0.0292 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.4253 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.4253 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.1857 | 0.4291 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0098 | 0.0093 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.4253 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0095 | 0.0091 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.4253 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.