Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 9.37 ug ml-1 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth dilution method | ChEMBL. | 17692520 |
MIC (functional) | = 18.75 ug ml-1 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | ChEMBL. | 17692520 |
MIC (functional) | = 18.75 ug ml-1 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | ChEMBL. | 17692520 |
MIC (functional) | = 18.75 ug ml-1 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | ChEMBL. | 17692520 |
MIC (functional) | > 100 ug ml-1 | Antibacterial activity against Mycobacterium tuberculosis H37Rv by nitrate reductase assay | ChEMBL. | 17692520 |
MIC (functional) | > 100 ug ml-1 | Antibacterial activity against Mycobacterium tuberculosis H37Rv by nitrate reductase assay | ChEMBL. | 17692520 |
MIC (functional) | = 150 ug ml-1 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 by broth dilution method | ChEMBL. | 17692520 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.