Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.2899 | 1 | 0.5 |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.2899 | 1 | 0.5 |
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.2899 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2899 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 12 % | Inhibition of Escherichia coli SoxS binding to DNA at 50 ug/mL | ChEMBL. | 17766109 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.