Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate receptor 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0191 | 0.7772 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus granulosus | glutamate receptor 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0137 | 0.3226 | 0.3226 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0217 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0111 | 0.0998 | 0.0998 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0111 | 0.0998 | 0.0998 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.05 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, E. coli (TH-13) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 0.05 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, E. coli (TH-13) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 0.39 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, Proteus mirabilis (121K) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 0.78 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, S. aureus (S-54K) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 0.78 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, S. aureus (ATCC90124) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 1.56 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, Proteus vulgaris (IID OX-19)was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 1.56 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, Serratia marcescens was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 6.25 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, E. coli (TH-397) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC (functional) | = 6.25 ug ml-1 | Growth inhibition against Beta lactamase producing bacteria, E. coli (TH-397) was determined for the compound in the combination with Ampicillin | ChEMBL. | 3039137 |
MIC50 (functional) | = 25 ug ml-1 | Minimum inhibitory concentration of the compound against 30 strains of E. coli | ChEMBL. | 3039137 |
MIC50 (functional) | = 25 ug ml-1 | Minimum inhibitory concentration of the compound against 30 strains of E. coli | ChEMBL. | 3039137 |
MIC70 (functional) | = 100 ug ml-1 | Minimum inhibitory concentration of the compound against 30 strains of E. coli | ChEMBL. | 3039137 |
MIC70 (functional) | = 100 ug ml-1 | Minimum inhibitory concentration of the compound against 30 strains of E. coli | ChEMBL. | 3039137 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.