Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | cytidine deaminase, putative | 0.0335 | 0.5 | 0.5 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0335 | 0.5 | 0.5 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0335 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0335 | 0.5 | 0.5 | |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.0335 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0335 | 0.5 | 0.5 |
Echinococcus multilocularis | cytidine deaminase | 0.0335 | 0.5 | 0.5 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0335 | 0.5 | 0.5 |
Leishmania major | cytidine deaminase-like protein | 0.0335 | 0.5 | 0.5 |
Echinococcus granulosus | cytidine deaminase | 0.0335 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0335 | 0.5 | 0.5 | |
Giardia lamblia | Cytidine deaminase | 0.0335 | 0.5 | 0.5 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0335 | 0.5 | 0.5 |
Trypanosoma brucei | cytidine deaminase | 0.0335 | 0.5 | 0.5 |
Mycobacterium ulcerans | cytidine deaminase | 0.0335 | 0.5 | 0.5 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0335 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 62 | Estrogenic effect in uterotrophic assay in immature mice at 1 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 86 | Estrogenic effect in uterotrophic assay in immature mice at 100 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 108 | Estrogenic effect in uterotrophic assay in immature mice at 25 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 140 | Estrogenic effect in uterotrophic assay in immature mice at 5 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 62 | Estrogenic effect in uterotrophic assay in immature mice at 1 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 86 | Estrogenic effect in uterotrophic assay in immature mice at 100 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 108 | Estrogenic effect in uterotrophic assay in immature mice at 25 ug dose | ChEMBL. | 3735317 |
Activity (functional) | = 140 | Estrogenic effect in uterotrophic assay in immature mice at 5 ug dose | ChEMBL. | 3735317 |
Inhibition (functional) | = 0 % | Anti-estrogenic effect in uterotrophic assay in immature mice at 1.0 ug dose | ChEMBL. | 3735317 |
Inhibition (functional) | = 0 % | Anti-estrogenic effect in uterotrophic assay in immature mice at 1.0 ug dose | ChEMBL. | 3735317 |
Inhibition (functional) | = 43.1 % | In vivo inhibition of hormone-dependent MXT mammary tumor in mice | ChEMBL. | 3735317 |
Inhibition (functional) | = 43.1 % | In vivo inhibition of hormone-dependent MXT mammary tumor in mice | ChEMBL. | 3735317 |
Inhibition (functional) | = 128.2 % | In vivo inhibition of uterine growth in hormone-dependent MXT mammary tumour bearing mice | ChEMBL. | 3735317 |
Inhibition (functional) | = 128.2 % | In vivo inhibition of uterine growth in hormone-dependent MXT mammary tumour bearing mice | ChEMBL. | 3735317 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.