Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanocortin 4 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0287 | 0.3964 | 1 |
Echinococcus multilocularis | jun protein | 0.0287 | 0.3964 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0233 | 0.3088 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0287 | 0.3964 | 1 |
Onchocerca volvulus | 0.0152 | 0.1764 | 0.596 | |
Mycobacterium ulcerans | putative regulatory protein | 0.0052 | 0.0142 | 0.5 |
Brugia malayi | bHLH-PAS transcription factor | 0.0052 | 0.0142 | 0.0142 |
Brugia malayi | hypothetical protein | 0.0225 | 0.296 | 0.296 |
Echinococcus granulosus | geminin | 0.0197 | 0.2495 | 0.6295 |
Schistosoma mansoni | jun-related protein | 0.0233 | 0.3088 | 1 |
Echinococcus multilocularis | geminin | 0.0197 | 0.2495 | 0.6295 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0052 | 0.0142 | 0.0357 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2495 | 0.8079 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0153 | 0.1774 | 0.4476 |
Brugia malayi | PAS domain containing protein | 0.0071 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0279 | 0.3836 | 0.3836 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0153 | 0.1774 | 0.4476 |
Brugia malayi | bZIP transcription factor family protein | 0.0287 | 0.3964 | 0.3964 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1764 | 0.1764 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2495 | 0.8079 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0134 | 0.1466 | 0.1466 |
Onchocerca volvulus | 0.0225 | 0.296 | 1 | |
Onchocerca volvulus | 0.0053 | 0.0152 | 0.0512 | |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0205 | 0.2626 | 0.8501 |
Loa Loa (eye worm) | hypothetical protein | 0.0658 | 1 | 1 |
Echinococcus granulosus | single minded 2 | 0.0052 | 0.0142 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1466 | 0.1466 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1476 | 0.1476 |
Echinococcus granulosus | jun protein | 0.0287 | 0.3964 | 1 |
Schistosoma mansoni | single-minded | 0.0071 | 0.044 | 0.1426 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.