Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.021 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.021 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.021 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.021 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.021 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.021 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.021 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.021 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 10 mM | Antibacterial activity against Vibrio harveyi MM77 mutant after 18 hrs | ChEMBL. | 18053731 |
MIC (functional) | = 10 mM | Antibacterial activity against Vibrio harveyi BB886 mutant after 18 hrs | ChEMBL. | 18053731 |
MIC (functional) | = 150 mM | Antibacterial activity against Vibrio harveyi BB170 mutant after 18 hrs | ChEMBL. | 18053731 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.