Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.5393 | 0.5 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0148 | 0.5393 | 1 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0148 | 0.5393 | 0.5 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.5393 | 0.5 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0148 | 0.5393 | 0.5 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0148 | 0.5393 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0148 | 0.5393 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.5393 | 0.5 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.5393 | 0.5 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0148 | 0.5393 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.5393 | 0.5 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0148 | 0.5393 | 1 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0148 | 0.5393 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0 | 0.5 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0148 | 0.5393 | 0.5 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0148 | 0.5393 | 0.5393 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0148 | 0.5393 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0148 | 0.5393 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0 | 0.5 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0148 | 0.5393 | 0.5 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0148 | 0.5393 | 1 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0148 | 0.5393 | 0.5 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0148 | 0.5393 | 0.5 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0148 | 0.5393 | 0.5 |
Plasmodium vivax | RNA helicase-1, putative | 0.0148 | 0.5393 | 0.5 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0148 | 0.5393 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.