Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0093 | 0.9121 | 1 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0077 | 0.6972 | 0.7644 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0024 | 0.0076 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | orexin receptor type 2 | 0.0024 | 0.0076 | 0.0083 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0093 | 0.9121 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0093 | 0.9121 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0084 | 0.7914 | 0.8677 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | serotonin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptide receptor | 0.0024 | 0.0076 | 0.0083 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0093 | 0.9121 | 0.9114 |
Echinococcus multilocularis | sex peptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0084 | 0.7914 | 0.8677 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | fmrfamide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0076 | 0.0083 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0082 | 0.7642 | 0.8365 |
Echinococcus multilocularis | somatostatin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | nmda type glutamate receptor | 0.008 | 0.7455 | 0.8174 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0082 | 0.7642 | 0.8379 |
Echinococcus multilocularis | serotonin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0024 | 0.0076 | 0.0083 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0082 | 0.7642 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | fmrfamide receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0024 | 0.0076 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | g-protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0093 | 0.9121 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0093 | 0.9121 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.008 | 0.7455 | 0.8174 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.9121 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0093 | 0.9121 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | allatostatin A receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | sex peptide receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0082 | 0.7642 | 0.8379 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | glutamate receptor NMDA | 0.0077 | 0.6972 | 0.7644 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | serotonin receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0024 | 0.0076 | 0.0083 |
Onchocerca volvulus | 0.0024 | 0.0076 | 0.5 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | hypothetical protein | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0024 | 0.0076 | 0.0083 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0076 | 0.0083 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0024 | 0.0076 | 0.0083 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.