Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nmda type glutamate receptor | 0.0088 | 0.1692 | 0.942 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0056 | 0.0838 | 0.5 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0084 | 0.1582 | 0.881 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0091 | 0.1796 | 1 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.0056 | 0.0838 | 0.4669 |
Trichomonas vaginalis | cdc25b, putative | 0.0056 | 0.0838 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0838 | 0.0128 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0091 | 0.1796 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0394 | 1 | 1 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.0056 | 0.0838 | 0.4669 |
Onchocerca volvulus | 0.0147 | 0.3305 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0394 | 1 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0394 | 1 | 1 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0084 | 0.1582 | 0.881 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0394 | 1 | 1 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0056 | 0.0838 | 0.5 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0056 | 0.0838 | 0.5 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0056 | 0.0838 | 0.5 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0056 | 0.0838 | 0.5 |
Trichomonas vaginalis | cdc25b, putative | 0.0056 | 0.0838 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.4775 | 0.437 |
Trichomonas vaginalis | cdc25c, putative | 0.0056 | 0.0838 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0109 | 0.2269 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0838 | 0.0128 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0088 | 0.1692 | 0.942 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0056 | 0.0838 | 0.5 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0056 | 0.0838 | 0.5 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0056 | 0.0838 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.