Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Echinococcus granulosus | serine:threonine protein kinase mig 15 | 0.0184 | 0.9935 | 1 |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Schistosoma mansoni | protein kinase | 0.0185 | 1 | 1 |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0083 | 0 | 0.5 |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Loa Loa (eye worm) | STE/STE20/MSN protein kinase | 0.0131 | 0.4673 | 0.4703 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0083 | 0 | 0.5 |
Echinococcus multilocularis | 0.0131 | 0.4673 | 1 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.9935 | 1 |
Onchocerca volvulus | 0.0083 | 0 | 0.5 | |
Echinococcus granulosus | protein kinase | 0.0131 | 0.4673 | 0.4703 |
Schistosoma mansoni | protein kinase | 0.0131 | 0.4673 | 0.4673 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 4.3 | Anti-inflammatory potency was measured in mice at 5 hours by modification of the croton oil ear assay | ChEMBL. | 3625707 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.