Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Aldose reductase | 0.0032 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0032 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0032 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0032 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0032 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0023 | 0.4815 | 0.4815 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0032 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus granulosus | aldehyde reductase | 0.0023 | 0.4815 | 0.4815 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Schistosoma mansoni | pol-related | 0.0032 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 1 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0032 | 1 | 0.5 |
Onchocerca volvulus | 0.0032 | 1 | 1 | |
Giardia lamblia | Aldose reductase | 0.0032 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0032 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0032 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0032 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.