Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0037 | 0.0037 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0352 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0134 | 0.255 | 0.255 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0352 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0037 | 0.0037 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Echinococcus multilocularis | insulin receptor | 0.0134 | 0.255 | 0.2522 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0453 | 0.0418 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0188 | 0.4377 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0134 | 0.255 | 0.2522 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0188 | 0.4377 | 0.5 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0134 | 0.255 | 0.2522 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.013 | 0.2393 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0134 | 0.255 | 0.255 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0188 | 0.4377 | 0.5 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0188 | 0.4377 | 0.4356 |
Onchocerca volvulus | 0.0188 | 0.4377 | 0.5 | |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0134 | 0.255 | 0.2522 |
Brugia malayi | Protein kinase domain containing protein | 0.0134 | 0.255 | 0.2522 |
Brugia malayi | Protein kinase domain containing protein | 0.0074 | 0.049 | 0.0455 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0352 | 1 | 1 |
Echinococcus granulosus | insulin receptor | 0.0134 | 0.255 | 0.2522 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0188 | 0.4377 | 0.4356 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0352 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.