Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0503 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.362 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.362 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.004 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0503 | 0.139 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.004 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.362 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 1 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 1 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0503 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.004 | 1 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.362 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.362 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 1 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0503 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.362 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.362 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.362 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.362 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.004 | 1 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.