Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin b | 0.0136 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0136 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0136 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0136 | 1 | 1 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0101 | 0.4302 | 0.4302 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0136 | 1 | 0.5 |
Echinococcus granulosus | caspase | 0.0101 | 0.4302 | 0.4302 |
Echinococcus granulosus | cathepsin b | 0.0136 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0136 | 1 | 1 |
Echinococcus multilocularis | caspase | 0.0101 | 0.4302 | 0.4302 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0136 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 1 | 0.5 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0101 | 0.4302 | 0.4302 |
Echinococcus granulosus | cathepsin b | 0.0136 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.