Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0134 | 1 | 0.5 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0134 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0134 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0134 | 1 | 0.5 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0134 | 1 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0134 | 1 | 0.5 |
Trypanosoma brucei | prolyl endopeptidase | 0.0134 | 1 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.012 | 0.8259 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0134 | 1 | 0.5 |
Echinococcus granulosus | prolyl endopeptidase | 0.0134 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0053 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0053 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Taste (binding) | -- 0 | Compound taste was tested with reference of sucrose sweetness; - - = very bitter | ChEMBL. | 6502596 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.