Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0058 | 0.1241 | 0.3293 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0004 | 0.0004 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0359 | 1 | 1 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0359 | 1 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0004 | 0.0004 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0359 | 1 | 1 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0004 | 0.0011 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0004 | 0.0004 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.3768 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0058 | 0.1241 | 0.3293 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0004 | 0.0011 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0004 | 0.0004 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0015 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0004 | 0.0004 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0004 | 0.0011 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0845 | 0.2242 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.1241 | 0.1241 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0359 | 1 | 1 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0359 | 1 | 0.5 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0004 | 0.0011 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0004 | 0.0033 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0015 | 0.0004 | 0.0011 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.3768 | 1 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0359 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0845 | 0.2242 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0004 | 0.0004 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0004 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0004 | 0.0004 |
Schistosoma mansoni | jumonji domain containing protein | 0.0058 | 0.1241 | 1 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0153 | 0.401 | 0.401 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0004 | 0.0011 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0 | 0.5 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0004 | 0.0011 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.1241 | 0.1241 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0058 | 0.1241 | 0.3293 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0845 | 0.6807 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0359 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.3768 | 0.3768 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.1241 | 0.1241 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.3768 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0845 | 0.6807 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0845 | 0.0845 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.3768 | 0.3768 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0359 | 1 | 1 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0004 | 0.0011 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0004 | 0.0004 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0015 | 0.0004 | 0.0011 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0004 | 0.0033 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0153 | 0.401 | 0.401 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0004 | 0.0004 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0004 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0845 | 0.2242 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.3768 | 0.3768 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0845 | 0.6807 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0004 | 0.0033 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0845 | 0.0845 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.1241 | 1 |
Plasmodium vivax | JmjC domain containing protein | 0.0015 | 0.0004 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0359 | 1 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.1241 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0058 | 0.1241 | 0.3293 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0004 | 0.0004 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0359 | 1 | 1 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0004 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0004 | 0.0004 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0845 | 0.2242 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0004 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0004 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0004 | 0.0004 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0004 | 0.0033 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0004 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.