Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0272 | 0.8987 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0611 | 0.068 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0611 | 0.068 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0047 | 0.0052 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0146 | 0.421 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0047 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.8987 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0047 | 0.029 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0252 | 0.0878 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.2378 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0146 | 0.421 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0611 | 0.068 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.2378 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.1012 | 0.1126 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0299 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0611 | 0.068 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.1618 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.2378 | 0.2646 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0299 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0616 | 0.0685 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0047 | 0.0052 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0252 | 0.0878 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0146 | 0.421 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.8987 | 1 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0272 | 0.8987 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.