Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.4811 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0296 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.015 | 0.4123 | 0.8571 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.3744 | 0.3643 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4123 | 0.8571 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.4379 | 0.5 |
Echinococcus granulosus | geminin | 0.0166 | 0.4775 | 0.9926 |
Onchocerca volvulus | 0.0097 | 0.1991 | 0.5 | |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.4379 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.3879 | 0.8124 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4123 | 0.8571 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.4811 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0169 | 0.0351 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4775 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0296 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4775 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.4123 | 0.8571 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.3879 | 0.8124 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.4123 | 0.8571 |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.4123 | 0.8571 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0296 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0169 | 0.0351 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.4811 | 1 |
Echinococcus multilocularis | geminin | 0.0166 | 0.4775 | 0.9926 |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.4123 | 0.8571 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0169 | 0.0351 |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.4123 | 0.8571 |
Loa Loa (eye worm) | carboxylesterase | 0.015 | 0.4123 | 0.8571 |
Echinococcus granulosus | carboxylesterase 5A | 0.015 | 0.4123 | 0.8571 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0169 | 0.0351 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.4123 | 0.8571 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.015 | 0.4123 | 0.8634 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.4811 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.015 | 0.4123 | 0.8571 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.4811 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.