Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.4037 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7164 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7164 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.4037 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.4037 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.4037 | 0.3031 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7164 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.4037 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.7164 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.7164 | 0.7164 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.7164 | 0.7164 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.4037 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.4037 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.7164 | 0.7164 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.4037 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0.7164 | 0.6687 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.7164 | 0.7164 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.4037 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.