Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | casein kinase I delta | 0.2438 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Onchocerca volvulus | 0.2438 | 1 | 1 | |
Echinococcus granulosus | casein kinase i | 0.2438 | 1 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.2438 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.2438 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.2438 | 1 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.2438 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.2438 | 1 | 1 |
Loa Loa (eye worm) | CK1/CK1/CK1-D protein kinase | 0.2438 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase i | 0.2438 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.2438 | 1 | 1 |
Echinococcus granulosus | casein kinase I delta | 0.2438 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.2438 | 1 | 0.5 |
Entamoeba histolytica | casein kinase 1, putative | 0.2438 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.2438 | 1 | 0.5 |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.2438 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.2438 | 1 | 1 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.2438 | 1 | 0.5 |
Leishmania major | casein kinase, putative | 0.2438 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2438 | 1 | 0.5 |
Brugia malayi | casein kinase I | 0.2438 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.2438 | 1 | 1 |
Trypanosoma brucei | casein kinase I, isoform 2 | 0.2438 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.2438 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.2438 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.2438 | 1 | 1 |
Trichomonas vaginalis | CK1 family protein kinase | 0.2438 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.2438 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 672 uM | Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3. | ChEMBL. | 9873411 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.