Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0159 | 0.1662 | 0.2481 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0334 | 0.5463 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0334 | 0.5463 | 0.5 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0334 | 0.5463 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0334 | 0.5463 | 0.4559 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0101 | 0.0408 | 0.0747 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0334 | 0.5463 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0543 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0334 | 0.5463 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0334 | 0.5463 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0334 | 0.5463 | 1 |
Plasmodium falciparum | protein kinase 5 | 0.0334 | 0.5463 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0334 | 0.5463 | 1 |
Echinococcus granulosus | cyclin dependent kinase | 0.0334 | 0.5463 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0159 | 0.1662 | 0.3042 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0159 | 0.1662 | 0.3042 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0334 | 0.5463 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.023 | 0.3218 | 0.1866 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.023 | 0.3218 | 0.5558 |
Trichomonas vaginalis | cyclins, putative | 0.0159 | 0.1662 | 0.3042 |
Trichomonas vaginalis | cyclins, putative | 0.0101 | 0.0408 | 0.0747 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0334 | 0.5463 | 1 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.023 | 0.3218 | 0.5558 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0334 | 0.5463 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0334 | 0.5463 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0159 | 0.1662 | 0.3042 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin B3, putative | 0.0101 | 0.0408 | 0.0747 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0334 | 0.5463 | 1 |
Onchocerca volvulus | 0.0159 | 0.1662 | 0.5 | |
Schistosoma mansoni | cyclin B | 0.0159 | 0.1662 | 0.2481 |
Trichomonas vaginalis | cyclin B, putative | 0.0159 | 0.1662 | 0.3042 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0159 | 0.1662 | 0.3042 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0334 | 0.5463 | 1 |
Echinococcus granulosus | cyclin B | 0.0159 | 0.1662 | 0.2481 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0159 | 0.1662 | 0.3042 |
Brugia malayi | Protein kinase domain containing protein | 0.0334 | 0.5463 | 0.4559 |
Trichomonas vaginalis | cyclin A, putative | 0.0159 | 0.1662 | 0.3042 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.5386 | 0.4466 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.023 | 0.3218 | 0.1866 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 0.5463 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0334 | 0.5463 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0101 | 0.0408 | 0.0747 |
Plasmodium vivax | protein kinase Crk2 | 0.0334 | 0.5463 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0334 | 0.5463 | 0.4559 |
Trichomonas vaginalis | cyclins, putative | 0.0159 | 0.1662 | 0.3042 |
Brugia malayi | cell division control protein 2 homolog | 0.0334 | 0.5463 | 0.4559 |
Entamoeba histolytica | cyclin, putative | 0.0159 | 0.1662 | 0.2481 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.0408 | 0.0747 |
Trichomonas vaginalis | cyclin D, putative | 0.0101 | 0.0408 | 0.0747 |
Echinococcus multilocularis | cyclin B | 0.0159 | 0.1662 | 0.2481 |
Schistosoma mansoni | cyclin B3 | 0.023 | 0.3218 | 0.5558 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0334 | 0.5463 | 0.4559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.