Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 10.5 | Compound was tested for effect of glycoside on superoxide production in rat heart sarcosomes | ChEMBL. | 3018245 |
Kd (binding) | = 2.07 | Tested for binding affinity of the compound per DNA base pair in rat | ChEMBL. | 3018245 |
MIC (functional) | = 50 ug ml-1 | Compound was tested for antibacterial activity against Staph. epidermitis ATCC 12228 | ChEMBL. | 3018245 |
MIC (functional) | = 50 ug ml-1 | Compound was tested for antibacterial activity against Strep. pyogenes ATCC 19615 | ChEMBL. | 3018245 |
MIC (functional) | = 50 ug ml-1 | Compound was tested for antibacterial activity against B. cereus WSU-60 | ChEMBL. | 3018245 |
MIC (functional) | = 50 ug ml-1 | Compound was tested for antibacterial activity against B. subtilis ATCC E6051 | ChEMBL. | 3018245 |
MIC (functional) | = 50 ug ml-1 | Compound was tested for antibacterial activity against C. diphtheria WSU | ChEMBL. | 3018245 |
MIC (functional) | = 100 ug ml-1 | Compound was tested for antibacterial activity against S. aureus ATCC 25923 | ChEMBL. | 3018245 |
MIC (functional) | = 200 ug ml-1 | Compound was tested for antibacterial activity against S. aureus ATCC 9144 | ChEMBL. | 3018245 |
MIC (functional) | = 200 ug ml-1 | Compound was tested for antibacterial activity against S. aureus WSU-196E | ChEMBL. | 3018245 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.