Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0576 | 0.6833 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0079 | 0.0825 | 0.1207 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.009 | 0.0958 | 0.1402 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0079 | 0.0825 | 0.1207 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0011 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.019 | 0.217 | 0.3175 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0576 | 0.6833 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.009 | 0.0958 | 0.1402 |
Giardia lamblia | Kinase, PLK | 0.0576 | 0.6833 | 1 |
Echinococcus multilocularis | Serine:threonine protein kinase PLK4 | 0.0452 | 0.5337 | 0.7811 |
Trypanosoma brucei | polo-like protein kinase | 0.0576 | 0.6833 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.009 | 0.0958 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0576 | 0.6833 | 0.6833 |
Echinococcus multilocularis | leucine rich repeat serine:threonine protein | 0.006 | 0.0593 | 0.0868 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0079 | 0.0825 | 0.1207 |
Echinococcus granulosus | Serine:threonine protein kinase PLK4 | 0.0452 | 0.5337 | 0.7811 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0576 | 0.6833 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0576 | 0.6833 | 1 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0 | 0.5 |
Echinococcus granulosus | leucine rich repeat serine:threonine protein | 0.006 | 0.0598 | 0.0875 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0011 | 0 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0576 | 0.6833 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.009 | 0.0958 | 0.0958 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0576 | 0.6833 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0958 | 0.1402 |
Loa Loa (eye worm) | TKL/LRRK protein kinase | 0.006 | 0.0593 | 0.0868 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.009 | 0.0958 | 0.1402 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0576 | 0.6833 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0593 | 0.0868 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.009 | 0.0958 | 0.1402 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.009 | 0.0958 | 0.1402 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0576 | 0.6833 | 0.5 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.019 | 0.217 | 0.3175 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0079 | 0.0825 | 0.1207 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0576 | 0.6833 | 1 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0011 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0576 | 0.6833 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.