Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | aminopeptidase, putative | 0.024 | 0.2129 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.024 | 0.2129 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.024 | 0.2129 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Giardia lamblia | Histone deacetylase | 0.0126 | 0.0579 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.024 | 0.2129 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.024 | 0.2129 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.0126 | 0.0579 | 0.0579 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0579 | 0.0654 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Trypanosoma brucei | histone deacetylase 1 | 0.0126 | 0.0579 | 0.2717 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0126 | 0.0579 | 0.2717 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.024 | 0.2129 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0126 | 0.0579 | 0.0654 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.024 | 0.2129 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0126 | 0.0579 | 0.0579 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.024 | 0.2129 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.0126 | 0.0579 | 0.0579 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0126 | 0.0579 | 0.2717 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0155 | 0.0975 | 0.4578 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0975 | 0.1102 |
Onchocerca volvulus | 0.0814 | 1 | 1 | |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0126 | 0.0579 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0574 | 0.6717 | 0.7593 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0126 | 0.0579 | 0.0654 |
Echinococcus granulosus | histone deacetylase 1 | 0.0126 | 0.0579 | 0.0579 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0126 | 0.0579 | 0.2717 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0126 | 0.0579 | 0.0579 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.024 | 0.2129 | 0.2129 |
Onchocerca volvulus | 0.024 | 0.2129 | 0.2129 | |
Loa Loa (eye worm) | aminopeptidase N | 0.024 | 0.2129 | 0.2407 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0126 | 0.0579 | 0.2717 |
Leishmania major | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Schistosoma mansoni | histone deacetylase | 0.0126 | 0.0579 | 0.2717 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.024 | 0.2129 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0126 | 0.0579 | 0.0579 |
Plasmodium falciparum | histone deacetylase 1 | 0.0126 | 0.0579 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.024 | 0.2129 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0975 | 0.1102 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.0975 | 0.0975 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0658 | 0.7871 | 0.8898 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0126 | 0.0579 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0126 | 0.0579 | 0.2717 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0155 | 0.0975 | 0.4578 |
Brugia malayi | hypothetical protein | 0.024 | 0.2129 | 0.2129 |
Echinococcus multilocularis | aminopeptidase N | 0.0814 | 1 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.024 | 0.2129 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0126 | 0.0579 | 0.2717 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0126 | 0.0579 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0729 | 0.8846 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Echinococcus granulosus | aminopeptidase N | 0.0814 | 1 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.024 | 0.2129 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0126 | 0.0579 | 0.0579 |
Brugia malayi | Peptidase family M1 containing protein | 0.024 | 0.2129 | 0.2129 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.024 | 0.2129 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.024 | 0.2129 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.024 | 0.2129 | 0.2129 |
Leishmania major | histone deacetylase, putative | 0.0126 | 0.0579 | 0.2717 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.