Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | casein kinase ii subunit alpha | 0.0079 | 1 | 0.5 |
Trypanosoma brucei | Casein kinase II | 0.0079 | 1 | 1 |
Trypanosoma cruzi | casein kinase II, putative | 0.0079 | 1 | 0.5 |
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.0079 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.0079 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Echinococcus granulosus | casein kinase ii subunit alpha | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0079 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.0079 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.0079 | 1 | 0.5 |
Onchocerca volvulus | 0.0053 | 0.648 | 0.5 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.0079 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 1 | 0.5 |
Plasmodium vivax | unspecified product | 0.0079 | 1 | 0.5 |
Leishmania major | casein kinase II, putative | 0.0079 | 1 | 0.5 |
Giardia lamblia | Kinase, CMGC CK2 | 0.0079 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 22 uM | Inhibition of Ca 2+ Influx in cultured rat cerebellar granule cells, mediated by ionotropic glutamate receptor AMPA | ChEMBL. | 11356106 |
IC50 (functional) | = 22 uM | Inhibition of Ca 2+ Influx in cultured rat cerebellar granule cells, mediated by ionotropic glutamate receptor AMPA | ChEMBL. | 11356106 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.