Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor II (thrombin) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0322 | 0 | 0.5 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0322 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0322 | 0 | 0.5 |
Trypanosoma cruzi | squalene synthase, putative | 0.1033 | 1 | 1 |
Trypanosoma brucei | squalene synthase, putative | 0.1033 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0322 | 0 | 0.5 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0322 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0322 | 0 | 0.5 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0322 | 0 | 0.5 |
Trypanosoma cruzi | squalene synthase, putative | 0.1033 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.