Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.1041 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.2633 | 0.2633 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.018 | 0 | 0.5 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0407 | 0.2633 | 0.2633 |
Onchocerca volvulus | 0.018 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1041 | 1 | 1 |
Echinococcus multilocularis | conserved hypothetical protein | 0.058 | 0.4645 | 1 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.1041 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.2633 | 0.2633 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0407 | 0.2633 | 1 |
Echinococcus granulosus | hypothetical protein | 0.061 | 0.4988 | 1 |
Brugia malayi | Serotonin receptor | 0.0416 | 0.2741 | 0.2741 |
Loa Loa (eye worm) | hypothetical protein | 0.036 | 0.2085 | 0.2085 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.