Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.3974 | 0.3974 |
Plasmodium falciparum | choline kinase | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0081 | 0.3974 | 0.3974 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0081 | 0.3974 | 0.3974 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.3974 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0081 | 0.3974 | 0.3974 |
Plasmodium vivax | choline kinase, putative | 0.0035 | 0 | 0.5 |
Toxoplasma gondii | phosphotransferase enzyme family protein | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0081 | 0.3974 | 0.3974 |
Echinococcus granulosus | acetylcholinesterase | 0.0081 | 0.3974 | 0.3974 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0081 | 0.3974 | 0.3974 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.3974 | 0.3974 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0144 | 0.9367 | 0.895 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0152 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3525 | 0.3525 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2857 | 0.2857 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.3974 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0081 | 0.3974 | 0.3974 |
Echinococcus granulosus | acetylcholinesterase | 0.0081 | 0.3974 | 0.3974 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.