Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.1306 | 0.1306 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.124 | 0.9493 |
Brugia malayi | Inositol-1 | 0.0038 | 0.1306 | 0.4419 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.2957 | 1 |
Echinococcus multilocularis | geminin | 0.0166 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.2957 | 0.2957 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.1306 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.1306 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.2957 | 0.2957 |
Brugia malayi | hypothetical protein | 0.0037 | 0.124 | 0.4194 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.1306 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.2957 | 0.2957 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.1039 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.2957 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.1306 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.124 | 0.9493 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.124 | 0.124 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.1306 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.124 | 0.9493 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.2957 | 0.2957 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.2957 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.1306 | 0.4419 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.2957 | 0.2957 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.1306 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.1306 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.1306 | 0.1306 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.124 | 0.124 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.2957 | 0.2957 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.124 | 0.124 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.2957 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.1306 | 0.1306 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.1306 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.1306 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.1306 | 0.1306 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.1039 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.1306 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.124 | 0.9493 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.2957 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.2957 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.1306 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.124 | 0.124 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.2957 | 0.2957 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.