Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0102 | 0.5 | 0.5 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0102 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.0102 | 0.5 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0102 | 0.5 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0102 | 0.5 | 0.5 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0102 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0102 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0102 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0102 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.5 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0102 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.0102 | 0.5 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0102 | 0.5 | 0.5 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0102 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0102 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 12.5 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv streptomycin resistant strain | ChEMBL. | 3934384 |
MIC (functional) | = 12.5 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv isonicotinic acid hydrazideresistant strain | ChEMBL. | 3934384 |
MIC (functional) | = 12.5 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv streptomycin resistant strain | ChEMBL. | 3934384 |
MIC (functional) | = 12.5 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv isonicotinic acid hydrazideresistant strain | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Antibacterial activity against Mycobacterium tuberculosis H37Rv. | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv kanamycin resistant strain | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Antibacterial activity against Mycobacterium kansasii | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Antibacterial activity against Mycobacterium intracellulare. | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Antibacterial activity against Mycobacterium tuberculosis H37Rv. | ChEMBL. | 3934384 |
MIC (functional) | = 25 ug ml-1 | Tested for antibacterial activity against Mycobacterium tuberculosis H37Rv kanamycin resistant strain | ChEMBL. | 3934384 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.