Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0213 | 0.4581 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0213 | 0.4581 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0213 | 0.4581 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0092 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0213 | 0.4581 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0213 | 0.4581 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0213 | 0.4581 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0213 | 0.4581 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0092 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0213 | 0.4581 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.0213 | 0.4581 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0213 | 0.4581 | 0.5 |
Toxoplasma gondii | PAN domain-containing protein | 0.0356 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0213 | 0.4581 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.001 uM | Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTP | ChEMBL. | 6694166 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.