Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0073 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Mycobacterium ulcerans | malate synthase G | 0.2203 | 1 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0073 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0073 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Onchocerca volvulus | 0.0011 | 0 | 0.5 | |
Schistosoma mansoni | carbonic anhydrase-related | 0.0027 | 0.0073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0073 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0027 | 0.0073 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0073 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.0027 | 0.0073 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0073 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0027 | 0.0073 | 0.5 |
Leishmania major | carbonic anhydrase-like protein | 0.0027 | 0.0073 | 0.5 |
Plasmodium falciparum | carbonic anhydrase | 0.0027 | 0.0073 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0027 | 0.0073 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0027 | 0.0073 | 0.5 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0027 | 0.0073 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0 | 0.5 |
Mycobacterium tuberculosis | Malate synthase G GlcB | 0.2203 | 1 | 0.5 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0027 | 0.0073 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0 | 0.5 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0027 | 0.0073 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0073 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0027 | 0.0073 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0027 | 0.0073 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0027 | 0.0073 | 1 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0027 | 0.0073 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0027 | 0.0073 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0073 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0027 | 0.0073 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0073 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.